CRISPR/Cas9-based screens: CRISPRko vs. CRISPRi

Learn more about the differences of Cas9-based CRISPRko (knockout) and CRISPRi (interference) screens

Would you like to know more about CRISPR knockout and interference screens?

A CRISPR knockout screen is a technique that uses CRISPR to systematically knock out or disrupt each gene in a genome to identify genes that are important for a particular biological process. Conversely, the CRISPR interference system uses a modified version of the CRISPR-Cas9 editing tool, which allows researchers to selectively turn off or “silence” genes of interest rather than editing them.