Learn more about Myllia and our powerful CROP-Seq (Perturb-Seq) technology enabling genetic screening for target discovery/validation

We utilise the CROP-Seq (for “CRISPR Droplet Sequencing”, also known as Perturb-Seq) workflow, developed by Myllia’s co-founder Christoph Bock, to map the impact of thousands of genetic perturbations on the global transcriptome at single-cell resolution, thus effectively establishing a paradigm for next generation CRISPR screens. Our powerful high-throughput screening approach has broad applications in identifying novel drug targets, elucidating unknown mechanisms of actions of drugs and understanding genetic variants linked to disease risk.

Meet Myllia’s R&D teams focused on genetic screening and computational biology:

The CRISPR screening team at Myllia Biotechnology GmbH in front of a brick wall in Vienna, Austria

Our end-to-end high-throughput screening platform for tailor-made CRISPR screens

Myllia has built an end-to-end genetic screening platform. We routinely conduct CROP-Seq screens using hundreds of thousands of single cells in one experiment and intend to scale the technology even further.

  • Customized assay development for cellular models, incl. primary cells
  • Proprietary guide RNA design algorithms for CRISPRn/i/a
  • Proprietary primer panel designs for targeted sequencing (TA-seq)
  • Cloning and manufacturing of lentiviral guide RNA libraries
  • Performance of the pooled CRISPR screens (high-throughput screening)
  • Single-cell library prep and NGS (WTA and TA-seq)
  • Bioinformatic analysis and target deconvolution

Get in touch with Myllia's leadership team and learn more about CROP-Seq - our genetic screening technology in single cells to fast-forward your target discovery projects

Myllia is located in Vienna, Austria